Next Gen Meds conference Draft Agenda

Our next conference is next here! Here is the draft agenda for the Next Gen Meds conference. Its in Washington DC from October 21st to Oct 23rd.

The conference is a real labor of love. I have spent months working on the program with plenty of help from some brilliant doctors. We want to especially mention the help of Dr. Fabrizio DeBenedetti, Dr. Alexei Grom, Dr. Scott Canna and Dr. Raphaela Goldbach-Mansky.

Next Gen Meds in MAS, SJIA, NLRC4 mutation and related diseases

• Location: Mandarin Oriental, Washington DC. (From 6 PM, Fri, Oct 21^st to 3 PM, Sun Oct 23^rd, 2016).

• Focus: SJIA, MAS, Still’s Disease, NLRC4 mutation, MAS+ILD and related diseases. Goal is to identify next gen drug options for patients who are not controlled by current drugs, by looking drugs in the pipeline for related diseases.

• Participants types:
  • Prominent Scientists focused on diseases listed above
  • Small group of parents of kids with diseases listed above
  • Scientists or representatives from drug companies
  • Regulators from USA and Europe

• Day 0 (Oct 21^th, Friday)
  • Informal get together in the evening
  • Keynote talk: Eric Hoffman

• Day 1 Oct 22^nd, Saturday (8.30 am to 5.30 pm)
  • Patients panel: to understand patient perspective & need for next gen therapies
  • Talk by FDA: Clinical trials process in USA (with a focus on rare diseases in pediatrics)
  • Talk by EMA: Clinical Trial process in Europe (with a focus on rare diseases in pediatrics)
  • Talks on potential next gen drugs and therapies
    • IL-18 Binding Protein – Tadekinig Alpha (from AB2Bio)
    • IL-17 Blocker – Secukinumab
    • IL1 Blockers – Anakinra updates
    • Interferon Gamma Blocker: NI-0501
    • Interferon α Blockers: Anifrolumab, Rontalizumab
    • Jak Inhibitors: Tofacitnib, Baricitnib,
    • Jak Inhibitors: Ruxolitnib
  • Panel: Discussion of drugs presented in previous session

• Day 2 (Oct 23^rd, Sunday: 30 am to 3.00 pm)
  • Breakfast session with patients: Focus group & Round Tables by investigators
  • Stem Cell Transplantation
    • Allogeneic Stem Cell Transplantation: Speakers from centers with recent experiences
    • Autologous Stem Cell Transplantation: Speaker from centers with recent experiences
  • Mesenchymal Stem Cell therapy: planned clinical trials in SJIA
  • Clinical Trials Round Table
  • Conference Wrap-up

Participants (confirmed): 

Physicians

• Ed Behrens
• Scott Canna
• Fabrizio DeBenedetti
• Adriana Alameida DeJesus
• Raphaela Goldbach Mansky
• Alexei Grom
• Rebecca Marsh
• Betsy Mellins
• Pierre Miossec
• Kim Nichols (remote)
• Peter Nigrovic
• Nora Singer
• Bas Vastert
• Paul Veys (remote)
• Lucy Wedderburn (remote)
• Nico Wulffraat

Parents

• Rashmi Sinha & Jon Boutelle
• Leah Nicholson Bush & Matt Bush
• Sabrina Dunlap & Robert Childs Jr.
• Kari Johnson Cupp
• Karen Alguire
• Tina Tamadon & Houman Tamadon

FDA / EMA

• Badrul Chowdhury (FDA)
• Sarah Yim (FDA)
• Nikolay Nikolov (FDA)
• Richard Veseley (EMA)

Pharmaceutical Companies

• Incyte: Guido Junge, Shephard, Mpofu
• Novimmune Cristina Min
• Sobi Christina Kaiser, Sven Ohlman
• AB2Bio Andrew Sleight, Fernando Cunha